Respostas Clínicas Cochrane

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As Respostas Clínicas Cochrane (RCCs) proporcionam um ponto de entrada amigável, digerível e clinicamente focado para as pesquisas rigorosas das revisões sistemáticas Cochrane. Elas são desenvolvidas para serem acionáveis e para respaldar a tomada de decisão no local de atendimento, e foram adicionadas a seções relevantes do texto principal do Best Practice.

  • In children with acute asthma, what are the effects of combined inhaled anticholinergics and short-acting beta2-agonists as initial treatment?
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  • What are the effects of adjunctive intravenous magnesium sulfate for children with acute asthma?
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  • For people with acute asthma, how does adding inhaled magnesium sulfate to beta-agonists (with or without ipratropium) affect outcomes?
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  • What are the effects of holding chambers (spacers) compared with nebulizers for beta-agonist treatment of acute asthma in children?
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  • What are the effects of adding intravenous beta-2 agonists to inhaled beta2-agonists in severe acute asthma in children?
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  • In children with acute asthma, what are the benefits and harms of anticholinergic therapy?
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  • For children with an acute exacerbation of asthma, what are the effects of second‐line inhaled bronchodilators?
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  • How does increased doses of inhaled corticosteroids (ICS) compare with stable doses for treating exacerbations of chronic asthma?
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  • How do intravenous beta‐agonists and aminophylline compare for treating acute severe asthma?
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  • In children with acute asthma, is there randomized controlled trial evidence to support the use of oral leukotriene receptor antagonists in addition to usual care ?
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  • For children and adolescents with mild to moderate asthma who are taking inhaled steroids, what serious adverse events are associated with formoterol?
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  • In people discharged from the emergency department following treatment for acute asthma, what are the benefits and harms of inhaled steroids?
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  • ​How do caseworker‐assigned discharge plans compare with non‐caseworker‐assigned plans for preventing readmission in children hospitalized for asthma exacerbations?
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