Síndrome hepatorrenal

Em um estudo realizado na Espanha, a probabilidade de que os pacientes com cirrose e ascite desenvolvam SHR foi de, aproximadamente, 40% em um período de 5 anos.[9]Gines A, Escorsell A, Gines P, et al. Incidence, predictive factors, and prognosis of the hepatorenal syndrome in cirrhosis with ascites. Gastroenterology. 1993 Jul;105(1):229-36. https://www.gastrojournal.org/article/0016-5085(93)90031-7/pdf?referrer=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2F http://www.ncbi.nlm.nih.gov/pubmed/8514039?tool=bestpractice.com Estudos subsequentes sugerem que de 12% a 20% dos pacientes hospitalizados com cirrose e lesão renal serão diagnosticados com SHR-LRA.​[10]Patidar KR, Belcher JM, Regner KR, et al. Incidence and outcomes of acute kidney injury including hepatorenal syndrome in hospitalized patients with cirrhosis in the US. J Hepatol. 2023 Dec;79(6):1408-17. http://www.ncbi.nlm.nih.gov/pubmed/37517455?tool=bestpractice.com ​[11]Garcia-Tsao G, Parikh CR, Viola A. Acute kidney injury in cirrhosis. Hepatology. 2008 Dec;48(6):2064-77. https://aasldpubs.onlinelibrary.wiley.com/doi/10.1002/hep.22605 http://www.ncbi.nlm.nih.gov/pubmed/19003880?tool=bestpractice.com [12]Nadim MK, Garcia-Tsao G. Acute kidney injury in patients with cirrhosis. N Engl J Med. 2023 Feb 23;388(8):733-45. http://www.ncbi.nlm.nih.gov/pubmed/36812435?tool=bestpractice.com