Câncer esofágico

Em regiões de alta incidência, como na província de Guangdong, na China, existem evidências de que o rastreamento citológico ou endoscópico seja adequado e útil. Pesquisas estão em andamento.[125]Chen R, Ma S, Guan C, et al. The National Cohort of Esophageal Cancer - Prospective Cohort Study of Esophageal Cancer and Precancerous Lesions based on High-Risk Population in China (NCEC-HRP): study protocol. BMJ Open. 2019 Apr 3;9(4):e027360. https://bmjopen.bmj.com/content/9/4/e027360 http://www.ncbi.nlm.nih.gov/pubmed/30948615?tool=bestpractice.com

Nos pacientes com esôfago de Barrett é indicada vigilância continuada para identificar lesões pré-malignas (displasia de alto grau) e carcinoma inicial in situ. Diretrizes recomendam rastreamento e vigilância a intervalos regulares para pacientes com esôfago de Barrett.[126]Qumseya B, Sultan S, Bain P, et al; ASGE Standards of Practice Committee. ASGE guideline on screening and surveillance of Barrett's esophagus. Gastrointest Endosc. 2019 Sep;90(3):335-59.e2. https://www.giejournal.org/article/S0016-5107(19)31704-3/fulltext http://www.ncbi.nlm.nih.gov/pubmed/31439127?tool=bestpractice.com [127]Shaheen NJ, Falk GW, Iyer PG, et al; American College of Gastroenterology. ACG clinical guideline: diagnosis and management of Barrett's esophagus. Am J Gastroenterol. 2016 Jan;111(1):30-50. https://journals.lww.com/ajg/Fulltext/2016/01000/ACG_Clinical_Guideline__Diagnosis_and_Management.17.aspx http://www.ncbi.nlm.nih.gov/pubmed/26526079?tool=bestpractice.com [128]Fitzgerald RC, di Pietro M, Ragunath K, et al. British Society of Gastroenterology guidelines on the diagnosis and management of Barrett's oesophagus. Gut. 2014 Jan;63(1):7-42. https://gut.bmj.com/content/63/1/7 http://www.ncbi.nlm.nih.gov/pubmed/24165758?tool=bestpractice.com [129]Shaheen NJ, Falk GW, Iyer PG, et al. Diagnosis and management of Barrett's esophagus: an updated ACG guideline. Am J Gastroenterol. 2022 Apr 1;117(4):559-87. https://journals.lww.com/ajg/Fulltext/2022/04000/Diagnosis_and_Management_of_Barrett_s_Esophagus_.17.aspx http://www.ncbi.nlm.nih.gov/pubmed/35354777?tool=bestpractice.com ​ Demonstrou-se que a ablação do esôfago de Barrett displásico reduz a progressão para neoplasia maligna invasiva.[130]Shaheen NJ, Sharma P, Overholt BF, et al. Radiofrequency ablation in Barrett's esophagus with dysplasia. N Engl J Med. 2009 May 28;360(22):2277-88. https://www.nejm.org/doi/full/10.1056/NEJMoa0808145 http://www.ncbi.nlm.nih.gov/pubmed/19474425?tool=bestpractice.com