O abscesso hepático é uma doença incomum. A incidência anual é de aproximadamente 3.6 por 100,000 nos EUA e no Reino Unido e varia de 8 a 20 casos por 100,000 internações hospitalares na maioria das séries.[4]Mohsen AH, Green ST, Read RC, et al. Liver abscess in adults: ten years experience in a UK centre. QJM. 2002 Dec;95(12):797-802.
https://academic.oup.com/qjmed/article/95/12/797/1572029/Liver-abscess-in-adults-ten-years-experience-in-a
http://www.ncbi.nlm.nih.gov/pubmed/12454322?tool=bestpractice.com
[6]Meddings L, Myers RP, Hubbard J, et al. A population-based study of pyogenic liver abscesses in the United States: incidence, mortality, and temporal trends. Am J Gastroenterol. 2010 Jan;105(1):117-24.
http://www.ncbi.nlm.nih.gov/pubmed/19888200?tool=bestpractice.com
[7]Huang CJ, Pitt HA, Lipsett PA, et al. Pyogenic hepatic abscess: changing trends over 42 years. Ann Surg. 1996 May;223(5):600-7.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1235191/pdf/annsurg00039-0160.pdf
http://www.ncbi.nlm.nih.gov/pubmed/8651751?tool=bestpractice.com
[8]Johannsen EC, Sifri CD, Madoff LC. Pyogenic liver abscesses. Infect Dis Clin North Am. 2000 Sep;14(3):547-63.
http://www.ncbi.nlm.nih.gov/pubmed/10987109?tool=bestpractice.com
A incidência anual de abscesso hepático pode ser mais alta em partes da Ásia (por exemplo, aproximadamente 15 casos por 100,000/ano em Taiwan).[9]Tsai FC, Huang YT, Chang LY, et al. Pyogenic liver abscess as endemic disease, Taiwan. Emerg Infect Dis. 2008 Oct;14(10):1592-600.
http://wwwnc.cdc.gov/eid/article/14/10/07-1254_article
http://www.ncbi.nlm.nih.gov/pubmed/18826824?tool=bestpractice.com
[10]Kim JK, Chung DR, Wie SH, et al. Risk factor analysis of invasive liver abscess caused by the K1 serotype Klebsiella pneumoniae. Eur J Clin Microbiol Infect Dis. 2009 Jan;28(1):109-11.
http://www.ncbi.nlm.nih.gov/pubmed/18663497?tool=bestpractice.com
A maioria dos casos de infecções amebianas ocorre nas Américas Central e do Sul, na África e na Ásia.[11]Petri WA Jr, Singh U. Diagnosis and management of amebiasis. Clin Infect Dis. 1999 Nov;29(5):1117-25.
https://academic.oup.com/cid/article/29/5/1117/337264/Diagnosis-and-Management-of-Amebiasis
http://www.ncbi.nlm.nih.gov/pubmed/10524950?tool=bestpractice.com
A amebíase (e subsequente abscesso hepático amebiano) em países desenvolvidos é observada mais comumente em imigrantes e viajantes de áreas endêmicas.[2]Centers for Disease Control and Prevention. CDC Yellow Book 2024: health information for international travel. Section 5: travel-associated infections & diseases - amebiasis. May 2023 [internet publication].
https://wwwnc.cdc.gov/travel/yellowbook/2024/infections-diseases/amebiasis#clinical
[12]Snider C, Petri WA Jr. Travel medicine. In: Rakel RE, ed. Conn's current therapy. 61st ed. New York, NY: W.B. Saunders; 2008:156-64.[13]Johnston V, Stockley JM, Dockrell D, et al; British Infection Society and the Hospital for Tropical Diseases. Fever in returned travellers presenting in the United Kingdom: recommendations for investigation and initial management. J Infect. 2009 Jul;59(1):1-18.
http://www.ncbi.nlm.nih.gov/pubmed/19595360?tool=bestpractice.com
A incidência de abscesso hepático aumenta com a idade, ocorrendo de modo um pouco mais frequente em homens que em mulheres.[3]Kaplan GG, Gregson DB, Laupland KB. Population-based study of the epidemiology of and the risk factors for pyogenic liver abscess. Clin Gastroenterol Hepatol. 2004 Nov;2(11):1032-8.
https://www.cghjournal.org/article/S1542-3565(04)00459-8/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/15551257?tool=bestpractice.com
[4]Mohsen AH, Green ST, Read RC, et al. Liver abscess in adults: ten years experience in a UK centre. QJM. 2002 Dec;95(12):797-802.
https://academic.oup.com/qjmed/article/95/12/797/1572029/Liver-abscess-in-adults-ten-years-experience-in-a
http://www.ncbi.nlm.nih.gov/pubmed/12454322?tool=bestpractice.com
[6]Meddings L, Myers RP, Hubbard J, et al. A population-based study of pyogenic liver abscesses in the United States: incidence, mortality, and temporal trends. Am J Gastroenterol. 2010 Jan;105(1):117-24.
http://www.ncbi.nlm.nih.gov/pubmed/19888200?tool=bestpractice.com
[9]Tsai FC, Huang YT, Chang LY, et al. Pyogenic liver abscess as endemic disease, Taiwan. Emerg Infect Dis. 2008 Oct;14(10):1592-600.
http://wwwnc.cdc.gov/eid/article/14/10/07-1254_article
http://www.ncbi.nlm.nih.gov/pubmed/18826824?tool=bestpractice.com
[14]Jepsen P, Vilstrup H, Schønheyder HC, et al. A nationwide study of the incidence and 30-day mortality rate of pyogenic liver abscess in Denmark, 1977-2002. Aliment Pharmacol Ther. 2005 May 15;21(1):1185-8.
http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2005.02487.x/full
http://www.ncbi.nlm.nih.gov/pubmed/15882238?tool=bestpractice.com
Estudos epidemiológicos mostraram que a incidência de abscesso hepático tem aumentado, enquanto a mortalidade tem estabilizado ou diminuído.[6]Meddings L, Myers RP, Hubbard J, et al. A population-based study of pyogenic liver abscesses in the United States: incidence, mortality, and temporal trends. Am J Gastroenterol. 2010 Jan;105(1):117-24.
http://www.ncbi.nlm.nih.gov/pubmed/19888200?tool=bestpractice.com
[9]Tsai FC, Huang YT, Chang LY, et al. Pyogenic liver abscess as endemic disease, Taiwan. Emerg Infect Dis. 2008 Oct;14(10):1592-600.
http://wwwnc.cdc.gov/eid/article/14/10/07-1254_article
http://www.ncbi.nlm.nih.gov/pubmed/18826824?tool=bestpractice.com
[14]Jepsen P, Vilstrup H, Schønheyder HC, et al. A nationwide study of the incidence and 30-day mortality rate of pyogenic liver abscess in Denmark, 1977-2002. Aliment Pharmacol Ther. 2005 May 15;21(1):1185-8.
http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2005.02487.x/full
http://www.ncbi.nlm.nih.gov/pubmed/15882238?tool=bestpractice.com
A tendência de aumento na incidência pode ser decorrente da disponibilidade de testes diagnósticos mais sensíveis que no passado (por exemplo, tomografia computadorizada) ou do aumento na prevalência de fatores predisponentes.