Criteria
Persistence of bleeding
Typical epistaxis:
Usually less profuse and responds to pressure, vasoconstrictor application, cautery, or nasal packing.
Recalcitrant epistaxis:
May be more profuse, with persistent bleeding despite nasal packing
More likely to occur in the context of an underlying coagulopathy, resulting in bleeding that is recalcitrant to all the normal measures
Possible causes of coagulopathy include primary disorders of coagulation (e.g., hemophilia), liver disease, and medications that impair clotting (e.g., warfarin, aspirin, nonsteroidal anti-inflammatory drugs)
Abnormal blood vessels; for example, patients with hereditary hemorrhagic telangiectasia have more frequent and more persistent epistaxis.
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