Dubin-Johnson syndrome

Chronic cholecystitis with cholelithiasis has been associated with DJS, but a definitive link has not been established.[5]Rastogi A, Krishnani N, Pandey R. Dubin-Johnson syndrome: a clinicopathologic study of twenty cases. Indian J Pathol Microbiol. 2006 Oct;49(4):500-4. http://www.ncbi.nlm.nih.gov/pubmed/17183837?tool=bestpractice.com [9]Skornick YG, Klausner JM, Lelcuk S, et al. Cholelithiasis in Dubin-Johnson syndrome. Surg Gynecol Obstet. 1983 Nov;157(5):447-9. http://www.ncbi.nlm.nih.gov/pubmed/6635916?tool=bestpractice.com [10]Sotelo-Avila C, Danis RK, Krafcik J, et al. Cholecystitis in a 17-year-old boy with recurrent jaundice since childhood. J Pediatr. 1988 Apr;112(4):668-74. http://www.ncbi.nlm.nih.gov/pubmed/3351696?tool=bestpractice.com

Cholecystitis

Subclinical cases of DJS often manifest during pregnancy and some studies have reported a higher frequency of fetal loss in women with DJS.[7]Seligsohn U, Shani M. The Dubin-Johnson syndrome and pregnancy. Acta Hepatogastroenterol. 1977 Jun;24(3):167-9. http://www.ncbi.nlm.nih.gov/pubmed/883465?tool=bestpractice.com [8]Di Zoglio JD, Cardillo E. The Dubin-Johnson syndrome and pregnancy. Obstet Gynecol. 1973 Oct;42(4):560-3. http://www.ncbi.nlm.nih.gov/pubmed/4742659?tool=bestpractice.com

Miscarriage