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Last reviewed: 15 Mar 2025
Last updated: 28 Jan 2025

Summary

Definition

History and exam

Other diagnostic factors

  • light-headedness/dizziness
  • postural/orthostatic hypotension
  • dysphagia
  • odynophagia
  • pain
  • melena
  • hematochezia
  • shock
  • signs of anemia

Risk factors

  • condition predisposing to retching, vomiting, and/or straining
  • chronic cough
  • hiatus hernia
  • retching during endoscopy or other instrumentation
  • significant alcohol use
  • previous instrumentation
  • age 30 to 50 years
  • male sex
  • use of aspirin or other nonsteroidal anti-inflammatory drugs
  • hiccups
  • blunt abdominal trauma
  • cardiopulmonary resuscitation

Diagnostic tests

1st tests to order

  • CBC
  • BUN
  • creatinine and electrolytes
  • LFT
  • prothrombin time (PT)/INR
  • PTT
  • crossmatching/blood grouping
  • flexible esophagogastroduodenoscopy (EGD)

Tests to consider

  • CT chest
  • CXR
  • angiography

Treatment algorithm

Contributors

Authors

Douglas G. Adler, MD, FACG, AGAF, FASGE

Professor of Medicine

Center Director

Center for Advanced Therapeutic Endoscopy (CATE)

Advent Health

Porter Adventist Hospital

Denver

CO

Disclosures

DGA is a consultant for Merit Medical, Cook Endoscopy, Olympus America, and Boston Scientific.

Acknowledgements

Dr Douglas Adler would like to gratefully acknowledge Dr Shilpa Reddy and Dr Juan Carlos Munoz, the previous contributors to this topic.

Disclosures

SR and JCM declare that they have no competing interests.

Peer reviewers

Joseph Sung, MD

Professor of Medicine

Department of Medicine and Therapeutics

Director

Institute of Digestive Disease

The Chinese University of Hong Kong

Hong Kong

Disclosures

JS declares that he has no competing interests.

Imtiyaz Mohammed, MD

Consultant Gastroenterologist

Sandwell General Hospital

Lyndon

West Bromwich

UK

Disclosures

IM declares that he has no competing interests.

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