Patient discussions

As part of conservative management, advise the patient to:[1][7]

  • Avoid drugs that could exacerbate the Brugada ECG pattern (for further information see: BrugadaDrugs.org: safe drug use and the Brugada syndrome Opens in new window).[18][51]

    • Antiarrhythmics (particularly sodium-channel blockers)

    • Psychotropic drugs

    • Anaesthetics

    • Certain over-the-counter drugs (e.g., antihistamines)

    • Illicit drugs (e.g., cannabis, cocaine).

  • Treat any fever promptly[18][51]

  • Avoid alcohol intoxication.[18][51]

In addition, patients should discuss new medications with their cardiologist as appropriate.

Reassure patients that exercise is not a normal trigger for ventricular arrhythmias in Brugada syndrome. However, a post-vagal state following exercise has been reported.

Advise patients to contact their care team urgently if they have palpitations, syncope, or seizures. In addition, if they have an implantable cardioverter defibrillator (ICD) they should also report any syncope or ICD shocks.

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