Recurrent aphthous stomatitis (episodic mouth ulcers)

For many patients with recurrent aphthous stomatitis (RAS), avoidance of trigger factors may reduce the frequency of episodes. Most patients will benefit from topical therapy during episodes of active ulceration. A small proportion of patients with severe RAS may require aggressive immunomodulatory treatment tailored to the individual patient.

For most patients with RAS, disease activity and frequency of episodes of active ulceration tends to decrease with time.