Epidemiology
Recurrent aphthous stomatitis (RAS) is prevalent mainly in childhood and early adulthood, with a natural history of spontaneous resolution with age.[2] If similar ulcers start later in life or are associated with fever or systemic disease, they may be aphthous-like ulcers rather than RAS.
RAS is the most common idiopathic intraoral ulcerative disease.[4] The prevalence of RAS varies according to the ethnic and socioeconomic group studied, with a range of 5% to 60% being reported.[5][6] The prevalence in the general population is accepted at approximately 20%.[7] It is slightly more prevalent in women and in higher socioeconomic groups.[8][9]
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