Last reviewed: 19 Mar 2025
Last updated: 07 Mar 2025
Summary
Definition
History and exam
Key diagnostic factors
- pain
- soft tissue swelling
- ecchymosis
- expanding hematoma
- impaired limb function
- inability to bear weight
- point tenderness
- deformity
- guarding
- wound overlying or near site of injury
- signs of vascular injury
- signs of acute compartment syndrome
- hypotension/hypovolemic shock
Other diagnostic factors
- altered nerve sensation
- impaired motor function
- bony crepitus
- callus
- reproduction of symptoms in stress fractures of the neck or shaft of the femur
Risk factors
- direct trauma
- indirect trauma
- osteoporosis (insufficiency fractures)
- chronic renal failure
- diabetes mellitus
- bone tumor (pathologic fractures)
- age >70 years
- age <30 years
- male sex (acute fractures)
- female sex (fatigue and insufficiency fractures)
- prolonged corticosteroid use (insufficiency fractures)
- low BMI (insufficiency fractures)
- history of recent fall (insufficiency fractures)
- prior fracture (insufficiency fractures)
- seizures (proximal humerus fracture)
- long-term bisphosphonate use
Diagnostic tests
Tests to consider
- MRI of area of interest without IV contrast
- noncontrast CT of fracture
- whole body bone scan with SPECT or SPECT/CT area of interest
- compartment pressure testing
- Doppler pressure (ankle/brachial systolic pressure index)
- ultrasound duplex scanning
- CT angiogram
- angiography
- dual-energy x-ray absorptiometry bone density scan
- whole-body CT
Treatment algorithm
INITIAL
ACUTE
Contributors
Authors
Philip H. Cohen, MD
Clinical Associate Professor of Medicine
UCLA David Geffen School of Medicine
Los Angeles
CA
Disclosures
PHC has given lectures for MCE Conferences, a medical education company, and received a stipend/free hotel room during the conference. MCE Conferences accepts no funding from pharmaceutical companies or other outside agencies, and PHC declares that the lectures have no impact on the topic.
Peer reviewers
Robert D. Golden, MD
Chief, Orthopaedic Surgery
MedStar Washington Hospital Center
Regional Chief
Orthopaedic Trauma Surgery
MedStar Orthopaedic Institute
Washington
DC
Disclosures
RDG declares that he has no competing interests.
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