Open-angle glaucoma often progresses without symptoms, and undetected glaucoma is both prevalent and treatable, suggesting a potential role for screening.[47]Soh Z, Yu M, Betzler BK, et al. The global extent of undetected glaucoma in adults: a systematic review and meta-analysis. Ophthalmology. 2021 Oct;128(10):1393-404.
https://www.aaojournal.org/article/S0161-6420(21)00277-3/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/33865875?tool=bestpractice.com
Population screening for open-angle glaucoma is, however, not cost-effective, and no country has established a viable national screening program.[13]Jayaram H, Kolko M, Friedman DS, et al. Glaucoma: now and beyond. Lancet. 2023 Nov 11;402(10414):1788-801.
http://www.ncbi.nlm.nih.gov/pubmed/37742700?tool=bestpractice.com
[48]Burr JM, Mowatt G, Hernandez R, et al. The clinical effectiveness and cost-effectiveness of screening for open angle glaucoma: a systematic review and economic evaluation. Health Technol Assess. 2007 Oct;11(41):iii-iv, ix-x, 1-190.
https://www.journalslibrary.nihr.ac.uk/hta/hta11410/#/full-report
http://www.ncbi.nlm.nih.gov/pubmed/17927922?tool=bestpractice.com
Targeted screening of high-risk groups is recommended (e.g., older adults, people with a family history of glaucoma, and African-Americans and Hispanics).[12]American Academy of Ophthalmology. Primary open-angle glaucoma suspect preferred practice pattern. Nov 2020 [internet publication].
https://www.aao.org/education/preferred-practice-pattern/primary-open-angle-glaucoma-suspect-ppp
Relatives should also be examined.
Subsequent to an updated evidence report and systematic review, the US Preventive Services Task Force (USPSTF) concluded that evidence is insufficient to assess the balance of benefits and harms of screening for open-angle glaucoma in asymptomatic adults 40 years or older.[49]Chou R, Selph S, Blazina I, et al. Screening for glaucoma in adults: updated evidence report and systematic review for the US Preventive Services Task Force. JAMA. 2022 May 24;327(20):1998-2012.
https://jamanetwork.com/journals/jama/fullarticle/2792610
http://www.ncbi.nlm.nih.gov/pubmed/35608575?tool=bestpractice.com
[50]US Preventive Services Task Force (USPSTF). Final recommendation statement. Primary open-angle glaucoma: screening. May 2022 [internet publication].
https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/primary-open-angle-glaucoma-screening
See Prognosis for information on risk stratification.