Colchicine may be of benefit for primary prevention of pericarditis and pericardial effusions in patients undergoing cardiac surgery.[32]Imazio M, Brucato A, Forno D, et al. Efficacy and safety of colchicine for pericarditis prevention. Systematic review and meta-analysis. Heart. 2012 Jul;98(14):1078-82. http://heart.bmj.com/content/98/14/1078.long http://www.ncbi.nlm.nih.gov/pubmed/22442198?tool=bestpractice.com [33]Imazio M, Brucato A, Rovere ME, et al. Colchicine prevents early postoperative pericardial and pleural effusions. Am Heart J. 2011 Sep;162(3):527-32. http://www.ncbi.nlm.nih.gov/pubmed/21884871?tool=bestpractice.com [34]Lutschinger LL, Rigopoulos AG, Schlattmann P, et al. Meta-analysis for the value of colchicine for the therapy of pericarditis and of postpericardiotomy syndrome. BMC Cardiovasc Disord. 2019 Sep 2;19(1):207. https://bmccardiovascdisord.biomedcentral.com/articles/10.1186/s12872-019-1190-4 http://www.ncbi.nlm.nih.gov/pubmed/31477020?tool=bestpractice.com [35]Malektojari A, Tahmasebipour R, Fadaeihosein M, et al. Pharmacological preventions and treatments for pericardial complications after open heart surgeries. Heart. 2025 Jan 23 [Epub ahead of print]. https://www.doi.org/10.1136/heartjnl-2024-324805 http://www.ncbi.nlm.nih.gov/pubmed/39848652?tool=bestpractice.com
Primary prevention
Secondary prevention
Colchicine may be of benefit for secondary prevention of pericarditis.[32][34][78]
[ 
]
[Evidence B]
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