Prognosis

Polycystic ovary syndrome (PCOS) is a chronic condition. There is no cure. Thus, management options are targeted at alleviating the signs and symptoms to reduce morbidity. Another goal of treatment is to prevent the development of complications such as type 2 diabetes and cardiovascular disease in later life.[188] There have been no clinical trials demonstrating the efficacy of any agent in terms of preventing complications. Many experts believe that weight loss and metformin may prevent diabetes and atherosclerosis.[189][190]​​​

In PCOS, therapy is generally continued throughout the reproductive years. If treatments are stopped during that time, symptoms generally recur. As women with PCOS get older or reach menopause, hyperandrogenic manifestations may improve as ovarian function declines, allowing withdrawal of therapies directed against hyperandrogenism.[191][192]​​​​ However, in some women with PCOS who enter menopause, clinical and biochemical hyperandrogenism may persist.[31][193]​​​​

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