Polycystic ovary syndrome

1990 National Institutes of Health criteria[1]Zawadzki JK, Dunaif A. Diagnostic criteria for polycystic ovary syndrome: towards a rational approach. In: Dunaif A, Givens JR, Haseltine F, et al., eds. Polycystic ovary syndrome. Cambridge, MA: Blackwell Scientific; 1992:377-84.

All of the following must be present:

• Hyperandrogenism and/or hyperandrogenemia

• Oligo- or anovulation

• Exclusion of other disorders.

2003 Rotterdam criteria[2]The Rotterdam ESHRE/ASRM-sponsored PCOS consensus workshop group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril. 2004 Jan;81(1):19-25. http://www.ncbi.nlm.nih.gov/pubmed/14711538?tool=bestpractice.com

Two of the following three must be present, and other disorders must be excluded:

• Hyperandrogenism and/or hyperandrogenemia

• Oligo- or anovulation

• Polycystic ovaries on ultrasound.

2006 Androgen Excess Society criteria[3]Azziz R, Carmina E, Dewailly D, et al. Positions statement: criteria for defining polycystic ovary syndrome as a predominantly hyperandrogenic syndrome: an Androgen Excess Society guideline. J Clin Endocrinol Metab. 2006 Nov;91(11):4237-45. https://academic.oup.com/jcem/article/91/11/4237/2656314 http://www.ncbi.nlm.nih.gov/pubmed/16940456?tool=bestpractice.com

All of the following must be present:

• Hyperandrogenism (hirsutism) and/or hyperandrogenemia

• Ovarian dysfunction: oligoanovulation and/or polycystic ovarian morphology

• Exclusion of other disorders.