Eosinophilic esophagitis

Eosinophilic esophagitis (EoE) is a chronic condition. Repeat esophagogastroduodenoscopy (EGD) to assess endoscopic and histologic disease activity is recommended after initiating or changing treatment, or with a change or worsening in clinical status.[3]Dellon ES, Gonsalves N, Hirano I, et al. ACG clinical guideline: evidenced based approach to the diagnosis and management of esophageal eosinophilia and eosinophilic esophagitis (EoE). Am J Gastroenterol. 2013 May;108(5):679-92. http://www.ncbi.nlm.nih.gov/pubmed/23567357?tool=bestpractice.com [28]Dellon ES, Liacouras CA. Advances in clinical management of eosinophilic esophagitis. Gastroenterology. 2014 Dec;147(6):1238-54. https://www.gastrojournal.org/article/S0016-5085(14)00980-9/fulltext http://www.ncbi.nlm.nih.gov/pubmed/25109885?tool=bestpractice.com ​​

Symptoms only modestly correlate with other measures of disease activity.[180]Safroneeva E, Straumann A, Coslovsky M, et al. Symptoms have modest accuracy in detecting endoscopic and histologic remission in adults with eosinophilic esophagitis. Gastroenterology. 2016 Mar;150(3):581-90. https://www.gastrojournal.org/article/S0016-5085(15)01621-2/fulltext http://www.ncbi.nlm.nih.gov/pubmed/26584601?tool=bestpractice.com ​ When EoE is in remission and well controlled, regular clinic visits (i.e., every 3-6 months in children, particularly to monitor growth and nutrition; and every 6-12 months in adults) are required. There are no formal recommendations on routine endoscopic surveillance, and this practice varies depending on the center.