Primary prevention

Lifestyle advice on diet, weight loss, or exercise may be recommended for patients with asymptomatic hyperuricemia.[52] There is an absence of evidence supporting the use of urate-lowering therapy in these patients.[52]

Secondary prevention

Hyperuricemia does not always lead to gout, but the incidence of gout increases with urate level.[9]

Patients with hyperuricemia and gout should avoid risk factors that may precipitate gout, such as excessive alcohol consumption, diuretic use, and weight gain.[142]

Patients with lymphoproliferative disorders requiring chemotherapy are given intravenous hydration and allopurinol to prevent hyperuricemia and complications such as acute renal failure due to uric acid nephropathy.[138]

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