Estimates of the prevalence and incidence of gout vary widely depending on the population studied and methods used. Globally reported prevalence ranges from <1% to 6.8%, and incidence ranges from 0.58 to 2.89 per 1000 person-years.[1]Dehlin M, Jacobsson L, Roddy E. Global epidemiology of gout: prevalence, incidence, treatment patterns and risk factors. Nat Rev Rheumatol. 2020 Jul;16(7):380-90.
http://www.ncbi.nlm.nih.gov/pubmed/32541923?tool=bestpractice.com
There are an estimated 41.2 million prevalent cases of gout worldwide, with 7.4 million incident cases per year. Incidence increased by 7.2%, and prevalence by 5.5%, between 1990 and 2017. The largest increases in prevalence were seen in the US, Canada and Oman.[2]Safiri S, Kolahi AA, Cross M, et al. Prevalence, incidence, and years lived with disability due to gout and its attributable risk factors for 195 countries and territories 1990-2017: a systematic analysis of the global burden of disease study 2017. Arthritis Rheumatol. 2020 Nov;72(11):1916-27.
https://www.doi.org/10.1002/art.41404
http://www.ncbi.nlm.nih.gov/pubmed/32755051?tool=bestpractice.com
Gout is more prevalent in men than women, and increases with age for both groups.[2]Safiri S, Kolahi AA, Cross M, et al. Prevalence, incidence, and years lived with disability due to gout and its attributable risk factors for 195 countries and territories 1990-2017: a systematic analysis of the global burden of disease study 2017. Arthritis Rheumatol. 2020 Nov;72(11):1916-27.
https://www.doi.org/10.1002/art.41404
http://www.ncbi.nlm.nih.gov/pubmed/32755051?tool=bestpractice.com
Prevalence varies geographically and racially, with the highest rates reported in Pacific countries, Australia and the US in 2017.[2]Safiri S, Kolahi AA, Cross M, et al. Prevalence, incidence, and years lived with disability due to gout and its attributable risk factors for 195 countries and territories 1990-2017: a systematic analysis of the global burden of disease study 2017. Arthritis Rheumatol. 2020 Nov;72(11):1916-27.
https://www.doi.org/10.1002/art.41404
http://www.ncbi.nlm.nih.gov/pubmed/32755051?tool=bestpractice.com
An estimated 9.3% to 13.9% of Maori men and 14.9% of Pacific island men suffer from severe gout.[3]Kuo CF, Grainge MJ, Zhang W, et al. Global epidemiology of gout: prevalence, incidence and risk factors. Nat Rev Rheumatol. 2015 Nov;11(11):649-62.
http://www.ncbi.nlm.nih.gov/pubmed/26150127?tool=bestpractice.com
[4]Ashiq K, Bajwa MA, Tanveer S, et al. A comprehensive review on gout: the epidemiological trends, pathophysiology, clinical presentation, diagnosis and treatment. J Pak Med Assoc. 2021 Apr;71(4):1234-8.
https://www.doi.org/10.47391/JPMA.313
http://www.ncbi.nlm.nih.gov/pubmed/34125777?tool=bestpractice.com
The prevalence of gout among US adults in 2016 was 3.9% (9.2 million people), of which 5.2% were male and 2.7% were female.[5]Chen-Xu M, Yokose C, Rai SK, et al. Contemporary prevalence of gout and hyperuricemia in the United States and decadal trends: the National Health And Nutrition Examination Survey, 2007-2016. Arthritis Rheumatol. 2019 Jun;71(6):991-9.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536335
http://www.ncbi.nlm.nih.gov/pubmed/30618180?tool=bestpractice.com
The annual incidence of gout in the US in people over 50 years of age has been estimated at 1.6 per 1000 in men and 0.3 per 1000 in women.[6]Abbott RD, Brand FN, Kannel WB, et al. Gout and coronary heart disease: the Framingham Study. J Clin Epidemiol. 1988;41(3):237-42.
http://www.ncbi.nlm.nih.gov/pubmed/3339376?tool=bestpractice.com
Data from primary care practices in the UK was used to estimate the prevalence (2.49%) and incidence (1.77 per 1000 person-years) of gout in 2012.[7]Kuo CF, Grainge MJ, Mallen C, et al. Rising burden of gout in the UK but continuing suboptimal management: a nationwide population study. Ann Rheum Dis. 2015 Apr;74(4):661-7.
https://www.doi.org/10.1136/annrheumdis-2013-204463
http://www.ncbi.nlm.nih.gov/pubmed/24431399?tool=bestpractice.com
When compared with incidence and prevalence rates from 1997, an increase of 63.9% in prevalence, and 29.6% in incidence was seen.[7]Kuo CF, Grainge MJ, Mallen C, et al. Rising burden of gout in the UK but continuing suboptimal management: a nationwide population study. Ann Rheum Dis. 2015 Apr;74(4):661-7.
https://www.doi.org/10.1136/annrheumdis-2013-204463
http://www.ncbi.nlm.nih.gov/pubmed/24431399?tool=bestpractice.com
Gout is rare in premenopausal women.[8]Hak AE, Curhan GC, Grodstein F, et al. Menopause, postmenopausal hormone use and risk of incident gout. Ann Rheum Dis. 2010 Jul;69(7):1305-9.
https://www.doi.org/10.1136/ard.2009.109884
http://www.ncbi.nlm.nih.gov/pubmed/19592386?tool=bestpractice.com