Screening

Mild HS may be present in 1 or more people per 2000 of the population and has been detected in as many as 1 in 150 men, and 1 in 800 women. However, these findings may not have clinical impact.[13] There is no reason to screen for HS apart from family members of a known case. In this situation, a combination of 4 simple tests (hemoglobin, bilirubin, reticulocyte count, and blood smear for spherocytes) has been documented to be a powerful tool for detection of affected family members.[27]

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