Mortality rates are higher after an incident hemorrhagic stroke (68%) than after ischemic stroke (57%).[5]Martin SS, Aday AW, Almarzooq ZI, et al. 2024 heart disease and stroke statistics: a report of US and global data from the American Heart Association. Circulation. 2024 Feb 20;149(8):e347-913.
https://www.ahajournals.org/doi/10.1161/CIR.0000000000001209
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[167]Koton S, Schneider AL, Rosamond WD, et al. Stroke incidence and mortality trends in US communities, 1987 to 2011. JAMA. 2014 Jul 16;312(3):259-68.
https://jamanetwork.com/journals/jama/fullarticle/1887762
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Only 20% to 30% of all patients are well enough to live independently by 3 to 6 months.[168]Carl Counsell, Surat. B, Martin. D, et al. Primary intracerebral haemorrhage in the Oxfordshire community stroke project: 2. Prognosis. Cerebrovasc Dis.1995 Feb; 5(1): 26-34.
https://karger.com/ced/article-abstract/5/1/26/59065/Primary-Intracerebral-Haemorrhage-in-the
[169]Katrak PH, Black D, Peeva V. Do stroke patients with intracerebral hemorrhage have a better functional outcome than patients with cerebral infarction? PM R. 2009 May;1(5):427-33.
http://www.ncbi.nlm.nih.gov/pubmed/19627929?tool=bestpractice.com
Hemorrhage volume is the strongest predictor of outcome.[170]Broderick JP, Brott TG, Duldner JE, et al. Volume of intracerebral hemorrhage. a powerful and easy-to-use predictor of 30-day mortality. Stroke. 1993 Jul;24(7):987-93.
https://www.ahajournals.org/doi/10.1161/01.str.24.7.987
http://www.ncbi.nlm.nih.gov/pubmed/8322400?tool=bestpractice.com
Advanced age, impaired consciousness at presentation, and rupture of the hematoma into the ventricular system are also associated with worse outcomes.[25]Hemphill JC 3rd, Bonovich DC, Besmertis L, et al. The ICH score: a simple, reliable grading scale for intracerebral hemorrhage. Stroke. 2001 Apr;32(4):891-7.
https://www.ahajournals.org/doi/10.1161/01.STR.32.4.891
http://www.ncbi.nlm.nih.gov/pubmed/11283388?tool=bestpractice.com
The Intracerebral Hemorrhage Score is a simple validated tool for predicting risk of death and functional outcome.[25]Hemphill JC 3rd, Bonovich DC, Besmertis L, et al. The ICH score: a simple, reliable grading scale for intracerebral hemorrhage. Stroke. 2001 Apr;32(4):891-7.
https://www.ahajournals.org/doi/10.1161/01.STR.32.4.891
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[171]Hemphill JC 3rd, Farrant M, Neill TA Jr. Prospective validation of the ICH Score for 12-month functional outcome. Neurology. 2009 Oct 6;73(14):1088-94.
http://www.ncbi.nlm.nih.gov/pubmed/19726752?tool=bestpractice.com
A similar score (the FUNC score) can be used to predict 3-month functional outcomes.[172]Rost NS, Smith EE, Chang Y, et al. Prediction of functional outcome in patients with primary intracerebral hemorrhage: the FUNC score. Stroke. 2008 Aug;39(8):2304-9.
https://www.ahajournals.org/doi/full/10.1161/strokeaha.107.512202
http://www.ncbi.nlm.nih.gov/pubmed/18556582?tool=bestpractice.com
Such clinical grading scales may be useful to stratify patients based on initial severity, but these numbers should be used with caution in clinical practice as they have been shown to overestimate the precise outcome.[173]Morgenstern LB, Zahuranec DB, Sánchez BN, et al. Full medical support for intracerebral hemorrhage. Neurology. 2015 Apr 28;84(17):1739-44.
http://www.ncbi.nlm.nih.gov/pubmed/25817842?tool=bestpractice.com
Guidelines recommend that all patients with intracerebral hemorrhage have access to multidisciplinary rehabilitation.[9]Greenberg SM, Ziai WC, Cordonnier C, et al. 2022 Guideline for the management of patients with spontaneous intracerebral hemorrhage: a guideline from the American Heart Association/American Stroke Association. Stroke. 2022 Jul;53(7):e282-361.
https://www.ahajournals.org/doi/full/10.1161/STR.0000000000000407
http://www.ncbi.nlm.nih.gov/pubmed/35579034?tool=bestpractice.com
One Cochrane review found that cardiorespiratory training (particularly involving walking) reduced disability, likely mediated by improved balance and mobility. Mixed training improved walking and balance, but to a lesser extent. Exercise interventions after stroke appeared to be safe.[174]Saunders DH, Sanderson M, Hayes S, et al. Physical fitness training for stroke patients. Cochrane Database Syst Rev. 2020 Mar 20;(3):CD003316.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD003316.pub7/full
http://www.ncbi.nlm.nih.gov/pubmed/32196635?tool=bestpractice.com