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Images

9

Retinoblastoma

MRI pattern of retinoblastoma with optic nerve involvement (sagittal enhanced T1-weighted sequence)

Aerts I, et al. Orphanet J Rare Dis 2006 Aug 25; 1: 31; licensed under CC BY 2.0

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6

Retinoblastoma

Two large retinoblastoma foci in the left eye; note the associated subretinal seeding

Personal collection of Dr Timothy Murray

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8

Retinoblastoma

Ultrasound of retinoblastoma

Aerts I, et al. Orphanet J Rare Dis 2006 Aug 25; 1: 31; licensed under CC BY 2.0

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2

Retinoblastoma

Light micrograph of a retinal section from a patient with retinoblastoma, a rare form of intraocular cancer. The tumor shows disrupted retinal architecture and infiltrative growth of atypical cells. Immunohistochemistry with anti-rhodopsin antibodies highlights areas of preserved photoreceptor differentiation within the retinal tissue. This staining aids in identifying residual retinal layers amidst the malignant cellular proliferation

​PR J. L. Kemeny, ISM/Science Photo Library; used with permission

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3

Retinoblastoma

Leukocoria (white pupillary light reflex) in the left eye of a patient with unilateral retinoblastoma

Personal collection of Dr Timothy Murray

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5

Retinoblastoma

Macular retinoblastoma in the right eye

Personal collection of Dr Timothy Murray

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10

Retinoblastoma

Aspect of trilateral retinoblastoma (MRI)

Aerts I, et al. Orphanet J Rare Dis 2006 Aug 25; 1: 31; licensed under CC BY 2.0

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1

Retinoblastoma

Histopathology of retinoblastoma. This image demonstrates the classical features of retinoblastoma, including densely packed, small, round tumor cells with hyperchromatic nuclei and scant cytoplasm, arranged in sheets. The absence of Flexner-Wintersteiner rosettes in this specimen does not preclude the diagnosis, as their presence is not obligatory. These histopathological features are typical of this aggressive retinal tumor and provide critical information for diagnosis, staging, and prognosis

​PR J. L. Kemeny, ISM/Science Photo Library; used with permission

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4

Retinoblastoma

Large retinoblastoma focus in the left eye

Personal collection of Dr Timothy Murray

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7

Retinoblastoma

Vitreous seeding associated with retinoblastoma

Personal collection of Dr Timothy Murray

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