Screening

Lesions may first appear on visible skin or mucous membranes and may be initially noticed by the patient.[4] Healthcare practitioners may consider screening the oral cavity in select patients; this is often the initial site of involvement in HIV-associated KS and can potentially be missed by the patient.[44]​ 

Clinical examination

Patients at risk of developing KS who should be examined for lesions include:

  • Older men of Mediterranean or Jewish origin

  • People living with HIV

  • Patients receiving immunosuppressive therapy

  • Transplant recipients

Human herpesvirus-8 (HHV-8) screening

HHV-8 screening is not currently recommended by international guidelines.

Screening solid organ transplant recipients and transplant donors for HHV-8 infection may increase knowledge regarding epidemiology and management of HHV-8-associated disease in transplant recipients.[33]

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