Epidemiology
Prolactinomas are the most common type of pituitary adenoma, constituting about 50% of these tumours.[1][2] Prolactin-secreting adenomas are more frequent in women between 20 and 50 years old, mainly during the child-bearing years, with an estimated ratio of frequency between women and men of 10:1.[1] This sex imbalance is not apparent in the older population, after the fifth decade of life, when the frequency of prolactinomas is similar in men and women.[2] The annual incidence rate of prolactinomas is between 2 and 5 new cases/100,000.[2] The prevalence of symptomatic microprolactinomas and macroprolactinomas is approximately 40 and 10 per 100,000, respectively.[2]
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