Endometrial cancer

5-year survival

The 5-year survival rate for endometrial cancer (based on US data between 2012 and 2018) by stage at diagnosis is:[230]National Cancer Institute. Surveillance epidemiology and end results (SEER). Cancer stat facts: uterine cancer. 2022 [internet publication]. https://seer.cancer.gov/statfacts/html/corp.html

• Localised (disease confined to the uterus): 94.9%

• Regional (disease spread regional lymph nodes): 69.8%

• Distant (metastatic disease): 18.4%

• Unknown (unstaged): 52.2%.

At diagnosis 67% of cases are localised, 20% are regional, 9% are distant, and 3% are unstaged.[230]National Cancer Institute. Surveillance epidemiology and end results (SEER). Cancer stat facts: uterine cancer. 2022 [internet publication]. https://seer.cancer.gov/statfacts/html/corp.html

Recurrence

Of cases that recur, 85% of cases of endometrial adenocarcinoma recur within the first 2 years.[132]Amant F, Moerman P, Neven P, et al. Endometrial cancer. Lancet. 2005 Aug 6-12;366(9484):491-505. http://www.ncbi.nlm.nih.gov/pubmed/16084259?tool=bestpractice.com Recurrences for early-stage disease occur at the vaginal cuff and pelvis.