Epidemiology

The global incidence of endometrial cancer is increasing, which may be related to the current obesity epidemic.[26] In 2019, there were approximately 435,000 new cases of endometrial cancer worldwide.[27] In the US in 2024, it is estimated that there will be 67,880 new cases of uterine cancer and an estimated 13,250 people will die of this disease.​​[28]

Median age at diagnosis is 64 years.[28]​ Based on US data from 2017 to 2021, the age-adjusted incidence is 28.0 cases per 100,000 women. Incidence (age-adjusted; 2017 to 2021) for non-Hispanic white women and non-Hispanic black women is 27.7 cases per 100,000 and 30.2 cases per 100,000, respectively.[28]​ Black women are substantially less likely to be diagnosed with localised-stage disease than white women (56% vs. 72%, respectively)​.[29]

In Europe, an estimated 124,874 cases of endometrial cancer were diagnosed in 2022, with 30,272 deaths from this cancer.[30]​​

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