Multiple myeloma (MM) is the second most common haematological cancer in high-income countries.[8]van de Donk NWCJ, Pawlyn C, Yong KL. Multiple myeloma. Lancet. 2021 Jan 30;397(10272):410-27.
http://www.ncbi.nlm.nih.gov/pubmed/33516340?tool=bestpractice.com
It is estimated that 35,780 new cases of MM and 12,540 associated deaths will occur in the US in 2024.[9]National Cancer Institute: Surveillance, Epidemiology, and End Results Program. Cancer stat facts: myeloma. 2023 [internet publication].
https://seer.cancer.gov/statfacts/html/mulmy.html
Median age at diagnosis is 69 years.[9]National Cancer Institute: Surveillance, Epidemiology, and End Results Program. Cancer stat facts: myeloma. 2023 [internet publication].
https://seer.cancer.gov/statfacts/html/mulmy.html
Incidence of MM in the US is higher among men than women (8.7 vs. 5.9 per 100,000 persons [2017-2021 data]).[9]National Cancer Institute: Surveillance, Epidemiology, and End Results Program. Cancer stat facts: myeloma. 2023 [internet publication].
https://seer.cancer.gov/statfacts/html/mulmy.html
Incidence is highest among non-Hispanic black people and lowest among non-Hispanic Asian/Pacific Islanders.[9]National Cancer Institute: Surveillance, Epidemiology, and End Results Program. Cancer stat facts: myeloma. 2023 [internet publication].
https://seer.cancer.gov/statfacts/html/mulmy.html
In Europe, the incidence of MM is 4.5 to 6.0 per 100,000 per year, with a mortality of 4.1 per 100,000 per year.[10]Moreau P, San Miguel J, Sonneveld P, et al. Multiple myeloma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2017 Jul 1;28(suppl 4):iv52-iv61.
http://www.ncbi.nlm.nih.gov/pubmed/28453614?tool=bestpractice.com
The median age at diagnosis is 72 years in Europe.[10]Moreau P, San Miguel J, Sonneveld P, et al. Multiple myeloma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2017 Jul 1;28(suppl 4):iv52-iv61.
http://www.ncbi.nlm.nih.gov/pubmed/28453614?tool=bestpractice.com