Emerging treatments

Inspiratory muscle strength training

Inspiratory muscle training (IMT) has been used to improve the strength of respiratory muscles in a wide range of medical conditions and athletic training. There are case reports of improvement through IMT with athletic adolescents diagnosed with exercise-induced paradoxical vocal fold motion (intermittent laryngeal obstruction) (EILO). In combination with medical and behavioural management, athletes were shown to have eliminated EILO and improved performance in their respective events with the athletes improving their maximum inspiratory pressure.[100][101][102][103]

Hypnosis

There is case reporting in which hypnosis was used as a diagnostic tool in a controlled environment. Self-hypnosis was guided to suggest a paradoxical vocal fold motion (intermittent laryngeal obstruction) attack during flexible fibre-optic nasendoscopy. This use may suggest a role as a form of treatment in addition to speech therapy and counselling.[104]

Electromyographic biofeedback

There is case reporting of use of surface electromyography (EMG) to treat paradoxical vocal fold motion (intermittent laryngeal obstruction) in which standard breathing recovery exercises were ineffective.[105]

Short-term intensive therapy

One study of 11 adolescent athletes suggests that short-term intensive therapy may be beneficial for athletes with paradoxical vocal fold motion (intermittent laryngeal obstruction).[106]

Olin exercise-induced laryngeal obstruction biphasic inspiration (EILOBI) breathing techniques

Olin EILOBI breathing techniques are designed to relieve EILO during high intensity exercise. The teaching process for these techniques consist of benchmarks of expectation setting, planning, splitting where biphasic breathing occurs, and learning forceful inhalation. A total of 66% of individuals with EILO perceived benefit from the use of these exercises.[93]

Buteyko breathing technique

In one study, 12 patients with EILO and hyperventilation who underwent the Buteyko breathing technique showed improvements in dyspnoea severity, resting heart rate, respiratory tidal minute volume, and end tidal CO₂.[107] Athletes may benefit from this technique.

Botulinum toxin

Botulinum toxin has been used in some studies in patients with severe symptoms to maintain an open airway, on as needed basis.[108][109]​ However, further research is required.

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