Atrial myxoma

Due to the potential of autosomal-dominant transmission, immediate family should be screened with echocardiogram. Genetic testing is not routinely performed, but patients with Carney's complex may have PRKAR1α gene mutations. As this disorder is transmitted in an autosomal dominant pattern, first degree relatives are at risk of developing cardiac myxomas. They may be offered genetic testing, so that they can be followed closely with periodic echocardiogram.