Case history
Case history #1
A 35-year-old man with a history of type 1 diabetes, illicit drug use, and noncompliance with insulin therapy presents with a 2- to 3-day complaint of left facial and eye pain, blurred vision, proptosis, and purplish discoloration of the periorbital area.
Case history #2
A 25-year-old woman with a recent diagnosis of acute myeloid leukemia undergoes induction chemotherapy resulting in prolonged neutropenia. Her course is complicated with neutropenic fever, for which she is treated with vancomycin and cefepime for 7 days with no definite source identified. Fever resolves in 48 hours and the antibiotics are stopped. She now has a dry cough, occasional hemoptysis, and febrile episodes. Computed tomography scan of the chest reveals nodular pulmonary infiltrates, which do not respond to empiric therapy with voriconazole.
Other presentations
Mucormycosis may present as a primary cutaneous disease involving surgical scars, catheter insertion sites, or burn wounds in immunosuppressed patients. A typical manifestation is necrosis of the involved skin, subcutaneous tissue and, in some cases, the fascia, muscles, and bone. Necrotizing fasciitis may complicate this disease. Cutaneous involvement, as a part of disseminated disease, is rare and is characterized by multiple nodular lesions, which rapidly progress, with development of an ecchymotic center. Gastrointestinal involvement is rare but fatal, often presenting with signs and symptoms of peritonitis due to bowel perforation.[7]
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