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MALT lymphoma

Gastric MALT lymphoma: infiltration of the gastric epithelium by neoplastic B-lymphocytes (CD20 staining, ×200)

From the collections of Dr R. Joshi and Dr C. McNamara; used with permission

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MALT lymphoma

Lung MALT lymphoma: lung parenchyma has been replaced by a neoplastic infiltrate of small lymphocytes; a follicle surrounded by neoplastic marginal zone cells can be recognized in the center of the image (hematoxylin and eosin [H&E] staining, ×200)

From the collections of Dr R. Joshi and Dr C. McNamara; used with permission

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MALT lymphoma

Gastric MALT lymphoma: normal gastric epithelium distorted by a neoplastic infiltrate of lymphocytes extending into the superficial gastric epithelium (hematoxylin and eosin [H&E] staining, × 200)

From the collections of Dr R. Joshi and Dr C. McNamara; used with permission

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MALT lymphoma

Infiltrate of lymphoid cells in the lung, confirming their B-cell origin (CD20 staining, ×200)

From the collections of Dr R. Joshi and Dr C. McNamara; used with permission

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MALT lymphoma

Lung MALT lymphoma: parts of this tumor demonstrate striking plasmacytic differentiation (CD138 staining, ×200)

From the collections of Dr R. Joshi and Dr C. McNamara; used with permission

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MALT lymphoma

MALT lymphoma has a polymorphous lymphoid infiltrate that can include small lymphocytes, monocytoid B cells, centrocyte-like cells and cells with plasmacytoid differentiation. Scattered immunoblasts and centroblast-like cells may also be seen

Hollie N, et al. J Clin Pathol. 2020; 73: 378-83; used with permission

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MALT lymphoma

Lung MALT lymphoma: residual respiratory epithelium has been distorted by infiltrating lymphocytes; the lymphoepithelial lesion (cytokeratin staining, ×200)

From the collections of Dr R. Joshi and Dr C. McNamara; used with permission

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