Meningioma

Data from the Central Brain Tumor Registry of the United States (CBTRUS) indicate that meningiomas account for 40.8% of all primary brain and other central nervous system (CNS) tumors in the US.[1]Ostrom QT, Price M, Neff C, et al. CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2016-2020. Neuro Oncol. 2023 Oct 4;25(12 suppl 2):iv1-99. https://academic.oup.com/neuro-oncology/article/25/Supplement_4/iv1/7289107 http://www.ncbi.nlm.nih.gov/pubmed/37793125?tool=bestpractice.com They are more common in females than males, comprising 50.6% and 27.3% of all primary CNS tumors, respectively. Tumors of the cerebral meninges are significantly more common than those of the spinal meninges (33.7% vs. 1.7%).

There is a higher age-adjusted incidence rate among black people than white, American Indian/Alaska Native, or Asian or Pacific Islander people. The incidence of meningioma increases with age in both sexes with median age of diagnosis at 67 years. There are approximately 38,000 new cases diagnosed annually in all age groups across the US.

80% of meningiomas are classified as World Health Organization (WHO) grade 1 (benign) tumors, while nearly 20% are WHO grade 2 (atypical). WHO grade 3 (malignant) meningiomas are rare, comprising only 1.5% of cases.