Complications
Complication
Timeframe
Likelihood
short term
low
Worsening of hypocalcemia after the start of vitamin D therapy for hypocalcemic rickets may occur.
Consider supplementing the breastfed infant with calcium during the first few days of therapy, to prevent the possibility of hypocalcemia and seizures attributed to hungry bones.[1]
short term
low
Possible adverse effects of vitamin D therapy include hypercalciuria, hypercalcemia, nephrocalcinosis, and intraocular calcifications.
Checking the urinary calcium-to-creatinine ratio and kidney function (i.e., serum creatinine) at follow-up visits is important. Renal ultrasound and ophthalmologic consultation (slit-lamp examination) may be performed in patients with hypercalciuria or hypercalcemia.[1][4]
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