Complications

Complication
Timeframe
Likelihood
short term
high

Found in type 2 Gaucher disease and mucopolysaccharidosis disorders.

short term
high

Found in types 2 and 3 Gaucher disease.

short term
high

Found in types 2 and 3 Gaucher disease.

short term
high

Found in type 2 Gaucher disease.

long term
medium

Found in adult type 1 Gaucher disease.

Parkinson disease

long term
medium

Found in adult type 1 Gaucher disease.

Cirrhosis

long term
medium

Found in Fabry disease.

Overview of stroke

long term
low

Found in adult type 1 Gaucher disease. Includes myeloma, lymphoma.

variable
high

Skeletal disease leading to bone pain, fracture, need for surgery. Found in adult types 1 and 3 Gaucher diseases.

variable
high

Found in Fabry disease.

variable
high

Found in Fabry disease.

variable
high

Found in Fabry disease.

variable
high

Found in Fabry disease.

variable
high

Found in Fabry disease.

variable
high

Development of antibodies to infused enzyme (males only with Fabry disease; females do not develop antibodies, perhaps because they are heterozygous and have circulating enzyme).

variable
high

Found in Pompe disease. Requires ventilator support.

variable
high

Found in Pompe disease.

variable
high

Found in Pompe disease. Development of antibodies to infused recombinant enzyme.

variable
high

Found in mucopolysaccharidosis disorders and Pompe disease.

variable
high

Found in mucopolysaccharidosis disorders.

variable
high

Found in mucopolysaccharidosis disorders.

variable
high

Found in mucopolysaccharidosis disorders.

variable
high

Found in mucopolysaccharidosis disorders. Due to stenosis at craniocervical region.

variable
high

Found in mucopolysaccharidosis disorders.

variable
high

Found in mucopolysaccharidosis disorders. Requires surgical assessment.

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