The prevalence worldwide is unknown due to the lack of standardized medical care and poor health care access in underdeveloped countries. In the US, an estimated 110,000 individuals are affected, but data suggest that prevalence is increasing.[6]Weyker D, Edelsberg J, Oster G, et al. Prevalence and economic burden of bronchiectasis. Clin Pulm Med. 2005;12:205.[7]Seitz AE, Olivier KN, Adjemian J, et al. Trends in bronchiectasis among medicare beneficiaries in the United States, 2000 to 2007. Chest. 2012 Aug;142(2):432-39.
http://journal.publications.chestnet.org/article.aspx?articleid=1262336
http://www.ncbi.nlm.nih.gov/pubmed/22302301?tool=bestpractice.com
Bronchiectasis is more common with advancing age, ranging from 4.2 per 100,000 people ages 18 to 34 years to 272 per 100,000 people over 75 years old.[6]Weyker D, Edelsberg J, Oster G, et al. Prevalence and economic burden of bronchiectasis. Clin Pulm Med. 2005;12:205. The economic burden of bronchiectasis is significant, with hospitalizations being the main driver, particularly in patients with frequent exacerbations or chronic Pseudomonas infection.[8]Goeminne PC, Hernandez F, Diel R, et al. The economic burden of bronchiectasis - known and unknown: a systematic review. BMC Pulm Med. 2019 Feb 28;19(1):54.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393984
http://www.ncbi.nlm.nih.gov/pubmed/30819166?tool=bestpractice.com
Bronchiectasis in children is increasingly being recognized.[9]Chang AB, Fortescue R, Grimwood K, et al. European Respiratory Society guidelines for the management of children and adolescents with bronchiectasis. Eur Respir J. 2021 Aug;58(2):2002990.
https://erj.ersjournals.com/content/58/2/2002990.long
http://www.ncbi.nlm.nih.gov/pubmed/33542057?tool=bestpractice.com
A study in New Zealand estimated the incidence to be 3.7 per 100,000 in children; incidence varied with ethnicity, with the highest rate being 17.8 per 100,000 in Pacific children.[10]Twiss J, Metcalfe R, Edwards E, et al. New Zealand national incidence of bronchiectasis "too high" for a developed country. Arch Dis Child. 2005 Jul;90(7):737-40.
http://www.ncbi.nlm.nih.gov/pubmed/15871981?tool=bestpractice.com
More than 60% of adults with bronchiectasis report symptoms from childhood, and these patients have worse disease and a poorer prognosis compared with patients with adult-onset bronchiectasis.[11]King PT, Holdsworth SR, Farmer M, et al. Phenotypes of adult bronchiectasis: onset of productive cough in childhood and adulthood. COPD. 2009 Apr;6(2):130-6.
https://www.tandfonline.com/doi/full/10.1080/15412550902766934
http://www.ncbi.nlm.nih.gov/pubmed/19378226?tool=bestpractice.com
Bronchiectasis is associated with a poor quality of life in both children and their parents, particularly when exacerbations are frequent.[9]Chang AB, Fortescue R, Grimwood K, et al. European Respiratory Society guidelines for the management of children and adolescents with bronchiectasis. Eur Respir J. 2021 Aug;58(2):2002990.
https://erj.ersjournals.com/content/58/2/2002990.long
http://www.ncbi.nlm.nih.gov/pubmed/33542057?tool=bestpractice.com