Complications
Mortality associated with hantavirus cardiopulmonary syndrome (HCPS) is between 30% and 50%, with death resulting from cardiogenic shock and cardiac arrhythmias.[8][18][5] There do not seem to be any effective early interventions.
Intensive care unit care with careful fluid management and inotropic support is essential, although not definitively shown to alter mortality.
Disseminated intravascular coagulation is possible in severe cases of HCPS infection, but is quite uncommon.
In one small series of 30 patients, 53% of HCPS survivors at a mean follow-up of 7.4 months had evidence of chronic kidney disease.[71]
Follow-up data on survivors are limited. Some patients experience residual pulmonary defects related to a decrease in small airway flow and a decrease in oxygen diffusing capacity. Fatigue and shortness of breath is a complaint.[5][44] Pulmonary dysfunction may persist for up to 1 year with subsequent resolution.[70]
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