Monitoring
Routine endoscopy to assess for disease progression in subjects with erosive or non-erosive GORD is not recommended.[1][3]
Endoscopic surveillance is recommended by most guidelines for patients with Barrett's oesophagus. This is based on longitudinal studies demonstrating that patients whose oesophageal cancers are detected by surveillance endoscopy are diagnosed at an earlier stage, and have improved survival, compared with similar patients who are not undergoing routine endoscopic surveillance.[127] Prospective clinical trials are lacking. Recommended surveillance intervals vary, according to the presence or absence of dysplasia.
Surveillance endoscopies should be performed while reflux symptoms are controlled on proton-pump inhibitor (PPI) therapy in order to heal oesophagitis and reduce the likelihood of interference by inflammation in interpretations of results.[127]
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