Steatotic liver disease

Any level of alcohol use may be harmful to liver health in patients with metabolic dysfunction-associated steatotic liver disease (MASLD).[80]Jarvis H, O'Keefe H, Craig D, et al. Does moderate alcohol consumption accelerate the progression of liver disease in NAFLD? A systematic review and narrative synthesis. BMJ Open. 2022 Jan 4;12(1):e049767. https://www.doi.org/10.1136/bmjopen-2021-049767 http://www.ncbi.nlm.nih.gov/pubmed/34983755?tool=bestpractice.com Patients should be counselled to abstain or keep alcohol intake below the risk threshold.[41]European Association for the Study of the Liver (EASL), European Association for the Study of Diabetes (EASD), European Association for the Study of Obesity (EASO). EASL-EASD-EASO clinical practice guidelines for the management of non-alcoholic fatty liver disease. J Hepatol. 2016 Jun;64(6):1388-402. https://www.doi.org/10.1016/j.jhep.2015.11.004 http://www.ncbi.nlm.nih.gov/pubmed/27062661?tool=bestpractice.com [68]National Institute for Health and Care Excellence. Non-alcoholic fatty liver disease (NAFLD): assessment and management. Jul 2016 [internet publication]. https://www.nice.org.uk/guidance/ng49 [80]Jarvis H, O'Keefe H, Craig D, et al. Does moderate alcohol consumption accelerate the progression of liver disease in NAFLD? A systematic review and narrative synthesis. BMJ Open. 2022 Jan 4;12(1):e049767. https://www.doi.org/10.1136/bmjopen-2021-049767 http://www.ncbi.nlm.nih.gov/pubmed/34983755?tool=bestpractice.com

Patients should also not exceed 2 g of paracetamol in a 24-hour period. Patients should be cautious about the use of over-the-counter or herbal medications. Patients with ascites should adhere to a strict 2 g sodium diet. Patients with cirrhosis need to seek urgent medical attention with any suggestion of decompensation, which includes abdominal distension, fevers, chills, confusion, haematemesis, haematochezia, or melaena. Patient information is available. British Liver Trust: liver conditions Opens in new window NIH: nonalcoholic fatty liver disease and NASH Opens in new window