Complications

Complication
Timeframe
Likelihood
long term
high

Commonly occur due to social, occupational, and forensic problems.

Overview of depression

long term
low

May result from renal cysts or other renal involvement. Dialysis may be required.

Chronic kidney disease

long term
low

May result from lymphangioleiomyomatosis, causing pulmonary hypertension, cor pulmonale, interstitial fibrosis, and restrictive lung disease.

variable
high

The sedative effects of concurrent anticonvulsant drug therapy and epileptic seizures often adversely affect strict regimens of consistent sleep routines and daily schedules. Adults may also be more prone to sleep apnoea.

A combination of behavioural and pharmacological treatments is generally needed.

Behavioural regimens include a consistent sleep-preparation routine, avoidance of stimulatory activity and stimulant drugs at time of sleep, minimisation of disruptions to daily routine and major life changes, consistent sleep quarters, use of transitional objects, use of appropriate ambience conducive to sleep, avoidance of parental co-sleeping, and the use of comforting and restful ambient sounds.

An initial introduction of nightly melatonin can be beneficial. More potent sedatives may additionally be needed, but efficacy may be limited.[77][86]

variable
high

Cognitive and behavioural problems can cause autistic spectrum disorders, aggressive behaviour, learning disabilities, and occupational, social, and relationship problems.

variable
low

May be caused by epileptic seizure or cardiac arrhythmia.

variable
low

May occur if an intracranial aneurysm ruptures.

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