Complications
Complication
Timeframe
Likelihood
short term
low
Worsening of hypocalcaemia after the start of vitamin D therapy for hypocalcaemic rickets may occur.
Consider supplementing the breastfed infant with calcium during the first few days of therapy, to prevent the possibility of hypocalcaemia and seizures attributed to hungry bones.[1]
short term
low
Possible adverse effects of vitamin D therapy include hypercalciuria, hypercalcaemia, nephrocalcinosis, and intra-ocular calcifications.
Checking the urinary calcium-to-creatinine ratio and kidney function (i.e., serum creatinine) at follow-up visits is important. Renal ultrasound and ophthalmological consultation (slit-lamp examination) may be performed in patients with hypercalciuria or hypercalcaemia.[1][4]
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