Monitoring

Long-term monitoring of AL amyloidosis involves serialised measurements of serum immunoglobulin free light chain, repeated serum and urine immunofixation electrophoresis, serum creatinine, and 24-hour total urinary protein.

Echocardiogram should be repeated every 6 months.

Serialised measurements of serum troponin and N-terminal pro-B-type natriuretic peptide (NT-proBNP) are useful in assessing the status of the heart, with rising levels indicating worsening cardiac status.

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