Criteria
Diagnostic criteria and categories for CPP arthritis[14][15]
1. Demonstration of CPP crystals in tissues or synovial fluid by definitive means, such as x-ray diffraction or chemical analysis.
2A. Identification of CPP crystals by morphological analysis using compensated polarising light microscopy.
2B. Typical calcifications on x-rays (cartilage calcification); heavy punctuate or linear calcifications in fibro-cartilage, articular (hyaline) cartilage, or joint capsules.
3A. Acute arthritis, especially of the knee or other large joints.
3B. Chronic arthritis of the knee, hip, wrist, elbow, shoulder, or metacarpophalangeals, particularly if accompanied by acute exacerbations, and if characterised by:
Involvement of uncommon sites for primary osteoarthritis
Radiographical appearance, including severe patellofemoral involvement
Subchondral cyst formation
Severe progressive joint degeneration with bony collapse
Variable and inconsistent osteophyte formation
Tendon calcifications, particularly of the Achilles, triceps, and obturator tendons
Axial skeletal involvement with subchondral cysts, disc calcification, and vacuum disc phenomena, as well as sacroiliac joint involvement.
Categories
Definite: criterion 1 or 2A and 2B
Probable: criterion 2A or 2B
Possible: criterion 3A or 3B.
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