Cochrane Clinical Answers

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Cochrane Clinical Answers (CCAs) provide a readable, digestible, clinically focused entry point to rigorous research from Cochrane systematic reviews. They are designed to be actionable and to inform decision making at the point of care and have been added to relevant sections of the main Best Practice text.

  • For people with chronic liver disease, what is the diagnostic test accuracy of magnetic resonance imaging (MRI) for the detection of resectable hepatocellular carcinoma (HCC)?
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  • How do hepatic resection, percutaneous injections or percutaneous laser ablation compare with radiofrequency ablation for improving outcomes in people with hepatocellular carcinoma?
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  • How does surgery compare with radiofrequency ablation in people with early- or very early-stage hepatocellular carcinoma?
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  • For people with unresectable hepatocellular carcinoma, how does external beam radiotherapy added to transarterial chemoembolization compare with transarterial chemoembolization alone?
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