Monitoring
People with gastric ulcer and H pylori should be followed up with a repeat endoscopy 6 to 8 weeks after beginning treatment, depending on the size of the lesion.[46] This enables the clinician to check ulcer healing and to rule out gastric cancer (because a small number of gastric cancers may present as gastric ulcers). Offer people with peptic ulcer (gastric or duodenal) and proven H pylori retesting for H pylori 6 to 8 weeks after beginning treatment, depending on the size of the lesion.[46] Patients with uncomplicated duodenal ulcers do not need follow-up endoscopy.
Ideally, the patient should stop proton-pump inhibitor (PPI) therapy for at least 14 days and antibiotics 28 days prior to eradication testing as these drugs suppress bacteria and can lead to false negatives.[46][48]
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