Glomerulonephritis

For glomerular diseases, the long-term prognosis tends to be better in patients who present with asymptomatic haematuria, low-grade proteinuria, and less severe glomerular involvement on kidney biopsy. Principal determinants of a relatively poor renal outcome include reduced estimated glomerular filtration rate (eGFR) at presentation, more severe proteinuria, lack of response to initial treatment, and an enhanced amount of fibrotic changes, such as interstitial fibrosis on initial kidney biopsy.