Monitoring
The major parameters that are serially monitored are urine sediment, protein excretion (usually estimated from the urine albumin-to-creatinine ratio or urine protein-to-creatinine ratio), and the serum creatinine concentration. These should be obtained at 2- to 4-week intervals during the initial therapy and then at 1- to 2-month intervals once drug therapy is stabilised and/or is being tapered. Disease activity for individual aetiologies can be monitored by their specific antibody titres every 2-4 weeks during the initial therapy and then at 1- to 2-month intervals, or whenever there are signs suggestive of recurrence.[49]
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