Hypoparathyroidism

Outlook varies depending on aetiology and severity of hypoparathyroidism.

Temporary or mild post-surgical hypoparathyroidism

Outlook is excellent for patients with temporary hypoparathyroidism. Suppressed but intrinsically normal glands in patients with chronic hypercalcaemia usually regain function within days to weeks of surgery. If the gland(s) remaining after neck surgery have been damaged or devascularised but remain viable, they will regain function in weeks to months, usually by 12 months.

Permanent hypoparathyroidism, all aetiologies

In the long-term management of patients with little to no remaining parathyroid hormone secretion, management is complicated by the often high doses of calcium and activated vitamin D therapy. Complications include ectopic calcifications, vitamin D intoxication, hypercalcaemia, renal stones, and insufficiency if over-treatment occurs. If under-treatment and hypocalcaemia occur, then symptoms of hypocalcaemia can manifest themselves. There are no long-term data available on life expectancy in patients with hypoparathyroidism.