The prevalence worldwide is unknown due to the lack of standardised medical care and poor health care access in underdeveloped countries. In the UK, an estimated 212,000 individuals are affected.[6]Snell N, Gibson J, Jarrold I, et al. Epidemiology of bronchiectasis in the UK: findings from the British Lung Foundation's 'Respiratory Health of the Nation' project. Respir Med. 2019 Oct - Nov;158:21-23.
http://www.ncbi.nlm.nih.gov/pubmed/31550642?tool=bestpractice.com
In the US, an estimated 110,000 individuals are affected, but data suggest that prevalence is increasing.[7]Weyker D, Edelsberg J, Oster G, et al. Prevalence and economic burden of bronchiectasis. Clin Pulm Med. 2005;12:205.[8]Seitz AE, Olivier KN, Adjemian J, et al. Trends in bronchiectasis among medicare beneficiaries in the United States, 2000 to 2007. Chest. 2012 Aug;142(2):432-39.
http://journal.publications.chestnet.org/article.aspx?articleid=1262336
http://www.ncbi.nlm.nih.gov/pubmed/22302301?tool=bestpractice.com
Bronchiectasis is more common with advancing age, ranging from 4.2 per 100,000 people aged 18 to 34 years to 272 per 100,000 people over 75 years old.[7]Weyker D, Edelsberg J, Oster G, et al. Prevalence and economic burden of bronchiectasis. Clin Pulm Med. 2005;12:205. The economic burden of bronchiectasis is significant, with hospitalisations being the main driver, particularly in patients with frequent exacerbations or chronic Pseudomonas infection.[9]Goeminne PC, Hernandez F, Diel R, et al. The economic burden of bronchiectasis - known and unknown: a systematic review. BMC Pulm Med. 2019 Feb 28;19(1):54.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393984
http://www.ncbi.nlm.nih.gov/pubmed/30819166?tool=bestpractice.com
Bronchiectasis in children is increasingly being recognised.[10]Chang AB, Fortescue R, Grimwood K, et al. European Respiratory Society guidelines for the management of children and adolescents with bronchiectasis. Eur Respir J. 2021 Aug;58(2):2002990.
https://erj.ersjournals.com/content/58/2/2002990.long
http://www.ncbi.nlm.nih.gov/pubmed/33542057?tool=bestpractice.com
A study in New Zealand estimated the incidence to be 3.7 per 100,000 in children; incidence varied with ethnicity, with the highest rate being 17.8 per 100,000 in Pacific children.[11]Twiss J, Metcalfe R, Edwards E, et al. New Zealand national incidence of bronchiectasis "too high" for a developed country. Arch Dis Child. 2005 Jul;90(7):737-40.
http://www.ncbi.nlm.nih.gov/pubmed/15871981?tool=bestpractice.com
More than 60% of adults with bronchiectasis report symptoms from childhood, and these patients have worse disease and a poorer prognosis compared with patients with adult-onset bronchiectasis.[12]King PT, Holdsworth SR, Farmer M, et al. Phenotypes of adult bronchiectasis: onset of productive cough in childhood and adulthood. COPD. 2009 Apr;6(2):130-6.
https://www.tandfonline.com/doi/full/10.1080/15412550902766934
http://www.ncbi.nlm.nih.gov/pubmed/19378226?tool=bestpractice.com
Bronchiectasis is associated with a poor quality of life in both children and their parents, particularly when exacerbations are frequent.[10]Chang AB, Fortescue R, Grimwood K, et al. European Respiratory Society guidelines for the management of children and adolescents with bronchiectasis. Eur Respir J. 2021 Aug;58(2):2002990.
https://erj.ersjournals.com/content/58/2/2002990.long
http://www.ncbi.nlm.nih.gov/pubmed/33542057?tool=bestpractice.com