Prognosis
DiGeorge syndrome is highly variable, and prognosis is determined by the severity of complications.[1] The disorder may be fatal if cardiac disease cannot be adequately treated or other severe anomalies are present. Alternatively, the patient may have only mild learning disabilities and go without a diagnosis. The outcome of each complication is similar to that in patients without DiGeorge syndrome.
Functional outcomes and levels of independent living in adults with DiGeorge syndrome are also very variable. Cognitive impairment and schizophrenia predict functional outcomes as an adult, but congenital heart disease or a history of mood or anxiety disorders do not. Support with social, communication, and vocational skills may help improve employability and independence.[113]
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