Emerging treatments
Topical quassia
The dried stem wood of quassia trees has active phytochemicals, which have antimicrobial and antifungal activity. A 4% topical quassia extract gel represents a new option for facial seborrheic dermatitis.[42]
Topical roflumilast foam
A highly potent and selective phosphodiesterase-4 (PDE4) inhibitor, roflumilast showed a 73.8% Investigator Global Assessment success rate after 8 weeks of treatment compared with a 40.9% success rate in patients treated with vehicle foam (P < 0.0001) in a phase 2 multicenter, multinational, double-blind, vehicle-controlled study of 226 adult patients.[43] It has now progressed to phase 3 trials.[44]
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