The rate of thoracolumbar fracture in blunt trauma patients is 4% to 7%.[12]Katsuura Y, Osborn JM, Cason GW. The epidemiology of thoracolumbar trauma: a meta-analysis. J Orthop. 2016 Dec;13(4):383-8.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963326
http://www.ncbi.nlm.nih.gov/pubmed/27504058?tool=bestpractice.com
[13]American College of Radiology. ACR appropriateness criteria: acute spinal trauma. 2024 [internet publication].
https://acsearch.acr.org/docs/69359/Narrative
The most common cause of thoracolumbar fractures are traffic accidents and falls.[9]Zileli M, Sharif S, Fornari M. Incidence and epidemiology of thoracolumbar spine fractures: WFNS Spine Committee recommendations. Neurospine. 2021 Dec;18(4):704-12.
https://e-neurospine.org/journal/view.php?doi=10.14245/ns.2142418.209
http://www.ncbi.nlm.nih.gov/pubmed/35000323?tool=bestpractice.com
[14]Glennie RA, Ailon T, Yang K, et al. Incidence, impact, and risk factors of adverse events in thoracic and lumbar spine fractures: an ambispective cohort analysis of 390 patients. Spine J. 2015 Apr 1;15(4):629-37.
http://www.ncbi.nlm.nih.gov/pubmed/25450658?tool=bestpractice.com
Increasing rates of thoracolumbar spine fractures have been seen in the US over the past several decades, despite a decline in other motor vehicle-related injuries, likely due to a combination of both increased detection of thoracolumbar spine injury and increased rate of seatbelt injury.[13]American College of Radiology. ACR appropriateness criteria: acute spinal trauma. 2024 [internet publication].
https://acsearch.acr.org/docs/69359/Narrative
A trend toward increased fractures rates in developing countries has been attributed to an increase of motor vehicle accidents.[9]Zileli M, Sharif S, Fornari M. Incidence and epidemiology of thoracolumbar spine fractures: WFNS Spine Committee recommendations. Neurospine. 2021 Dec;18(4):704-12.
https://e-neurospine.org/journal/view.php?doi=10.14245/ns.2142418.209
http://www.ncbi.nlm.nih.gov/pubmed/35000323?tool=bestpractice.com
A 2018 study described a mean age of 49.1 ± 17.7 years.[15]Li B, Sun C, Zhao C, et al. Epidemiological profile of thoracolumbar fracture (TLF) over a period of 10 years in Tianjin, China. J Spinal Cord Med. 2019 Mar;42(2):178-83.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419675
http://www.ncbi.nlm.nih.gov/pubmed/29595401?tool=bestpractice.com
Older patients may present with thoracolumbar fractures as a result of low-energy trauma, for example, falls from standing, due to diminished bone mineralization commonly present in older patient populations, and coexisting osteoporosis.[9]Zileli M, Sharif S, Fornari M. Incidence and epidemiology of thoracolumbar spine fractures: WFNS Spine Committee recommendations. Neurospine. 2021 Dec;18(4):704-12.
https://e-neurospine.org/journal/view.php?doi=10.14245/ns.2142418.209
http://www.ncbi.nlm.nih.gov/pubmed/35000323?tool=bestpractice.com
[10]Wendt K, Nau C, Jug M, et al. ESTES recommendation on thoracolumbar spine fractures: January 2023. Eur J Trauma Emerg Surg. 2024 Aug;50(4):1261-75.
https://link.springer.com/article/10.1007/s00068-023-02247-3
Falls are about 2.8 times more likely to cause injury in older people (ages >65 years) than in people <65 years.[16]Acton PA, Farley T, Freni LW, et al. Traumatic spinal cord injury in Arkansas, 1980 to 1989. Arch Phys Med Rehabil. 1993 Oct;74(10):1035-40.
http://www.ncbi.nlm.nih.gov/pubmed/8215853?tool=bestpractice.com
Up to 70% of osteoporotic fractures remain undiagnosed.[17]Royal Osteoporosis Society. Clinical guidance for the effective identification of vertebral fractures. Mar 2020 [internet publication].
https://strwebprdmedia.blob.core.windows.net/media/5inhyz5i/ros-vertebral-fractures-guidelines.pdf
See Osteoporotic spinal compression fractures.
Thoracolumbar spine trauma is more common in males than in females. Reported male-to-female ratios vary; one 2018 study detailed a ratio of 1.4:1, whereas a 1991 paper gave a ratio of 4:1.[15]Li B, Sun C, Zhao C, et al. Epidemiological profile of thoracolumbar fracture (TLF) over a period of 10 years in Tianjin, China. J Spinal Cord Med. 2019 Mar;42(2):178-83.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419675
http://www.ncbi.nlm.nih.gov/pubmed/29595401?tool=bestpractice.com
[18]Parsons KC. The impact of spinal cord injury on long-term survival. J Insur Med. 1991 Winter;23(4):227.
http://www.ncbi.nlm.nih.gov/pubmed/10148505?tool=bestpractice.com
This shift may be explained by females more frequently taking part in higher-risk activities today than they did in previous decades.
Pediatric patients comprise 1% to 5% of spinal injury admissions.[19]Hamilton MG, Myles ST. Pediatric spinal injury: review of 174 hospital admissions. J Neurosurg. 1992 Nov;77(5):700-4.
http://www.ncbi.nlm.nih.gov/pubmed/1403110?tool=bestpractice.com
In pediatric populations, the spinal cord can be injured without disruption of the spinal column - a condition defined as SCIWORA (spinal cord injury without radiologic abnormality).[20]Carroll T, Smith CD, Liu X, et al. Spinal cord injuries without radiologic abnormality in children: a systematic review. Spinal Cord. 2015 Dec;53(12):842-8.
https://www.nature.com/articles/sc2015110
http://www.ncbi.nlm.nih.gov/pubmed/26169164?tool=bestpractice.com
[21]Boese CK, Oppermann J, Siewe J, et al. Spinal cord injury without radiologic abnormality in children: a systematic review and meta-analysis. J Trauma Acute Care Surg. 2015 Apr;78(4):874-82.
http://www.ncbi.nlm.nih.gov/pubmed/25807412?tool=bestpractice.com
Children may be more susceptible to SCIWORA than adults because of the relatively higher elasticity of spinal ligaments allowing for greater deformation forces on the spinal cord, without fracturing or dislocating the vertebrae.[20]Carroll T, Smith CD, Liu X, et al. Spinal cord injuries without radiologic abnormality in children: a systematic review. Spinal Cord. 2015 Dec;53(12):842-8.
https://www.nature.com/articles/sc2015110
http://www.ncbi.nlm.nih.gov/pubmed/26169164?tool=bestpractice.com
SCIWORA involves the thoracolumbar spine less frequently than the cervical spine.[20]Carroll T, Smith CD, Liu X, et al. Spinal cord injuries without radiologic abnormality in children: a systematic review. Spinal Cord. 2015 Dec;53(12):842-8.
https://www.nature.com/articles/sc2015110
http://www.ncbi.nlm.nih.gov/pubmed/26169164?tool=bestpractice.com
[22]Srinivasan V, Jea A. Pediatric thoracolumbar spine trauma. Neurosurg Clin N Am. 2017 Jan;28(1):103-14.
http://www.ncbi.nlm.nih.gov/pubmed/27886872?tool=bestpractice.com
SCIWORA occurs in 42% of patients under 9 years old, and 8% of patients 15-17 years old.[23]Dickman CA, Zabramski JM, Hadley MN, et al. Pediatric spinal cord injury without radiographic abnormalities: report of 26 cases and review of the literature. J Spinal Disord. 1991 Sep;4(3):296-305.
http://www.ncbi.nlm.nih.gov/pubmed/1802160?tool=bestpractice.com
Thoracic and lumbar fractures account for around 48% and 32% of all spinal injuries, respectively, and most occur between thoracic spine T11,T12, and lumbar spine L1.[24]Alhadhoud M, Alsiri N. The epidemiology of spinal fractures in a level 2 trauma center in Kuwait. SAGE Open Med. 2021;9:20503121211051932.
https://journals.sagepub.com/doi/10.1177/20503121211051932
http://www.ncbi.nlm.nih.gov/pubmed/34671474?tool=bestpractice.com
[25]Li Y, Yan L, Cai S, et al. The prevalence and under-diagnosis of vertebral fractures on chest radiograph. BMC Musculoskelet Disord. 2018 Jul 18;19(1):235.
https://bmcmusculoskeletdisord.biomedcentral.com/articles/10.1186/s12891-018-2171-y
http://www.ncbi.nlm.nih.gov/pubmed/30021567?tool=bestpractice.com
Multilevel spinal fractures are present in around one quarter of spinal injury patients.[25]Li Y, Yan L, Cai S, et al. The prevalence and under-diagnosis of vertebral fractures on chest radiograph. BMC Musculoskelet Disord. 2018 Jul 18;19(1):235.
https://bmcmusculoskeletdisord.biomedcentral.com/articles/10.1186/s12891-018-2171-y
http://www.ncbi.nlm.nih.gov/pubmed/30021567?tool=bestpractice.com
[26]Hebert JS, Burnham RS. The effect of polytrauma in persons with traumatic spine injury. A prospective database of spine fractures. Spine (Phila Pa 1976). 2000 Jan;25(1):55-60.
http://www.ncbi.nlm.nih.gov/pubmed/10647161?tool=bestpractice.com
Most isolated fractures are related to osteoporosis.[27]Riggs BL, Melton LJ. Osteoporosis: etiology, diagnosis, and management. Philadelphia, PA: Lippincott-Raven; 1995.[Figure caption and citation for the preceding image starts]: MRI lumbar spine: sagittal view (T2-weighted sequence) showing an osteoporotic fracture of the T12 vertebral bodyFrom the personal collection of Dr B. Nurboja and Mr D. Choi [Citation ends].
Around 35% to 50% of patients with spinal injuries have associated neurologic involvement.[14]Glennie RA, Ailon T, Yang K, et al. Incidence, impact, and risk factors of adverse events in thoracic and lumbar spine fractures: an ambispective cohort analysis of 390 patients. Spine J. 2015 Apr 1;15(4):629-37.
http://www.ncbi.nlm.nih.gov/pubmed/25450658?tool=bestpractice.com
[28]Riggins RS, Kraus JF. The risk of neurologic damage with fractures of the vertebrae. J Trauma. 1977 Feb;17(2):126-33.
http://www.ncbi.nlm.nih.gov/pubmed/846019?tool=bestpractice.com
Spinal cord injuries occur in the thoracic region in 17% of cases, and the lumbar region in 20% to 24% of cases.[29]Tator CH, Duncan EG, Edmonds VE, et al. Neurological recovery, mortality and length of stay after acute spinal cord injury associated with changes in management. Paraplegia. 1995 May;33(5):254-62.
http://www.ncbi.nlm.nih.gov/pubmed/7630650?tool=bestpractice.com
Patients with these injuries commonly have other associated injuries, such as concurrent multiple system injuries (80%) and head injuries (41%).[30]Vaccaro AR, An HS, Lin S, et al. Noncontiguous injuries of the spine. J Spinal Disord. 1992 Sep;5(3):320-9.
http://www.ncbi.nlm.nih.gov/pubmed/1520991?tool=bestpractice.com
[31]Davidoff G, Roth E, Morris J, et al. Assessment of closed head injury in trauma related spinal cord injury. Paraplegia. 1986 Apr;24(2):97-104.
http://www.ncbi.nlm.nih.gov/pubmed/3714296?tool=bestpractice.com